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17-Hydroxycorticosteroids, Urine

Measurement of 17-hydroxycorticosteroids in urine is used to control adrenal cortex function.

More information

17-Hydroxycorticosteroids (17-OHCS) are degradation products of cortisone and hydrocortisone and which can be used as a measure of the production of these molecules and the function of the adrenal cortex. 17-Hydroxycorticosteroids are carbon compounds having a dihydroxyacetone group in the seventeenth carbon molecule. Cortisone and hydroxycortisone regulate, but are not limited to, carbohydrate and protein metabolism and are involved in the regulation of ACTH secretion.

What are the clinical indications for the measurement of 17-Hydroxycorticosteroids?
 
  • Dehydration
  • Weight loss
  • Change in mental state
  • Motion sickness
  • Vomiting
  • Diarrhea
  • Fatigue
  • Longing for savory foods
  • Facial edema (full moon)
  • Kyphosis (buffalo hibernation)
  • Abnormal hair growth

What do the results of 17-Hydroxy Corticosteroids control in urine mean?
An elevated level of 17-hydroxycorticosteroids in the urine may mean:

  • Cushing's syndrome
  • Adrenal cancer
  • Hyperpituitarism
  • Eclampsia
  • Hyperthyroidism
  • Taking certain medications and nutritional supplements

A reduced level of 17-hydroxycorticosteroids in urine may mean:

  • Addison's disease
  • Androgenetic syndrome
  • Hypothyroidism
  • Hypopituitarism
  • Taking certain medications and nutritional supplements
Possible Interpretations of Pathological Values
 
  • Increase: Antley-Bixler syndrome, congenital adrenal hyperplasia, spermatoma, hirsuitism, ovarian cysts, ovarian tumors, polycystic ovary syndrome (PCOS), masculinization. Medications: steroids in premature infants, metformin.
  • Decrease: No clinical significance.
Important Note

Laboratory test results are the most important parameter for the diagnosis and monitoring of all pathological conditions. 70%-80% of diagnostic decisions are based on laboratory tests. Correct interpretation of laboratory results allows a doctor to distinguish "healthy" from "diseased".

Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be interpreted in relation to each individual case and family history, clinical findings and the results of other laboratory tests and information. Your personal physician should explain the importance of your test results.

At Diagnostiki Athinon we answer any questions you may have about the test you perform in our laboratory and we contact your doctor to get the best possible medical care.

Additional information
Results Time5 - 7 Days
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