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Iron (Fe), Serum

Serum iron is used in the assessment of conditions related to the production and destruction of red blood cells, as well as metabolism and transport of iron.

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Iron (Fe) is an inorganic ion, mainly found in hemoglobin and acts as a carrier of oxygen from the lungs to tissues and indirectly participates in the return of carbon dioxide to the lungs. Although the primary source of iron in the body is food, only a small portion of the iron in the food can and is absorbed. Iron is stored in the liver and in the reticuloendothelial system in the form of ferritin and hemosiderin and is released when needed to meet the body's requirements. Although iron levels are assumed to be higher in the morning due to daily fluctuations, studies have shown that limiting morning sampling does not improve the reliability of the test results.

Toxicity can occur with an iron intake in excess of 20 mg / kg body weight.

Possible Interpretations of Pathological Values
  • Increase: Acute hepatitis, aplastic anemia, blood transfusions, hemochromatosis, hemolytic anemia, hepatitis, lead poisoning, nephritis, pernicious anemia, multicellularemia, ferroblastic anemia, thalassemia6, thalassemia. Medications: Alcohol (wine, ethanol), cefotaxime, chloramphenicol, estrogen, iron sulfate, methimazole, methotrexate
  • Decrease: Blood loss, burns, cancer, gastrectomy, infection, iron deficiency anemia, kwashiorkor, malabsorption, nephrosis, post-operative conditions, pregnancy, rheumatoid arthritis, schizophrenia (chronic),Tetralogy of Fallot, uremia. Medications: Metformin, Allopurinol, Aspirin, Cholestyramine, Corticotropin, Pergolide, Progestagens, Risperidone, Testosterone






Important Note

Laboratory test results are the most important parameter for the diagnosis and monitoring of all pathological conditions. 70%-80% of diagnostic decisions are based on laboratory tests. Correct interpretation of laboratory results allows a doctor to distinguish "healthy" from "diseased".

Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be interpreted in relation to each individual case and family history, clinical findings and the results of other laboratory tests and information. Your personal physician should explain the importance of your test results.

At Diagnostiki Athinon we answer any questions you may have about the test you perform in our laboratory and we contact your doctor to get the best possible medical care.

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