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Lymphocytic Choriomeningitis Virus (LCMV), Molecular Detection

Molecular control for LCMV is used for laboratory documentation of the disease by this virus.

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Lymphocytic choriomeningitis is a viral infectious disease transmitted by rodents (usually mice) and presented as aseptic meningitis, encephalitis or meningoencephalitis. The causative agent of the disease is the LCMV, a member of the Arenaviridae family.

The virus can be transmitted after exposure to urine, feces, saliva or other materials from infected rodents. Transmission can occur when these materials are introduced directly into the skin or mucous membranes of the nose, eyes and mouth or possibly through bait from an infected rodent. Transmission from person to person has not been reported, with the exception of vertical transmission from the infected mother to the fetus and rarely during organ transplantation.

In the first stage of the disease, the most common laboratory findings are a low white blood cell count (leukopenia) and a low platelet count (thrombocytopenia). Liver enzymes (transaminases) in the serum may be slightly elevated. After the onset of neurological symptoms during the second phase, there is usually an increase in albumin levels, an increase in the number of white blood cells and a decrease in glucose levels in the cerebrospinal fluid.



Important Note

Laboratory test results are the most important parameter for the diagnosis and monitoring of all pathological conditions. 70%-80% of diagnostic decisions are based on laboratory tests. Correct interpretation of laboratory results allows a doctor to distinguish "healthy" from "diseased".

Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be interpreted in relation to each individual case and family history, clinical findings and the results of other laboratory tests and information. Your personal physician should explain the importance of your test results.

At Diagnostiki Athinon we answer any questions you may have about the test you perform in our laboratory and we contact your doctor to get the best possible medical care.


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