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Tricyclic Antidepressants (TCA), Urine

This test checks the urine for the presence of tricyclic antidepressants.

Tricyclic antidepressants are a term that describes a group of drugs with a similar cyclic chemical structure, often used to treat depression in the long run. Tricyclic antidepressants act by inhibiting the uptake of norepinephrine (noradrenaline) and serotonin in the central nervous system and have anticholinergic properties. They are metabolized in the liver, with varying levels of half-life and peak about 4-8 hours after oral administration.

Toxicity: Confusion, excitement, hallucinations, epileptic seizures, coma, arrhythmia, hyperthermia, flushing, mydriasis, death.

The test detects the drugs nortriptyline, nordoxepine, trimipramine, amitriptyline, promazine, desipramine, imipramine, chlomipramine, doxepin, mprotilin, promethazine.




Important Note

Laboratory test results are the most important parameter for the diagnosis and monitoring of all pathological conditions. 70%-80% of diagnostic decisions are based on laboratory tests. Correct interpretation of laboratory results allows a doctor to distinguish "healthy" from "diseased".

Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be interpreted in relation to each individual case and family history, clinical findings and the results of other laboratory tests and information. Your personal physician should explain the importance of your test results.

At Diagnostiki Athinon we answer any questions you may have about the test you perform in our laboratory and we contact your doctor to get the best possible medical care.

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