Antibody testing against reticulin is no longer performed at Diagnostiki Athinon.
Antibodies against tissue transglutaminase, intramuscular and anti-deaminated gliadin (DGP) antibodies are used to control gluten, celiac disease and herpetic dermatitis.
Please go to the corresponding exams.
- Intramammary IgA Antibodies and Intramammary IgG Antibodies
- Tissue Transglutaminase IgA Antibodies and Tissue Transglutaminase IgG Antibodies
- Glamadin IgA Antibodies and Glamadin IgG Antibodies
Celiac disease is a genetically inherited autoimmune digestive disease and is quite common in Europe. Members of families with herpetic dermatitis or celiac disease have an increased risk of celiac disease. Celiac disease is characterized by a permanent gluten intolerance. Gluten is a complex protein found in processed foods derived from wheat, barley and rye. When gluten is absorbed, the immune system triggers an inflammatory reaction on the mucosa of the small intestine. A gluten-free diet can completely stop the immune response. When the patient is on a gluten free diet, the small intestine fixes its lesions and the antibodies decrease and eventually disappear. However, reintroduction of gluten into the diet stimulates the immune response again.
Patients with celiac disease produce a variety of autoantibodies, including intramuscular (EMA), tissue transglutaminase (tTG), gliadin and reticulin antibodies, as part of the immune response. IgA antibodies are usually predominant although patients may also produce IgG autoantibodies. The levels of these antibodies decrease after a gluten-free diet. Reticulin antibodies do not have the sensitivity and specificity of intramuscular and tissue transglutaminase (tTG) antibodies in the detection of celiac disease. Serological tests offer a minimally invasive option for the rapid identification of patients who may have celiac disease and who should undergo a biopsy to confirm the diagnosis.
Laboratory test results are the most important parameter for the diagnosis and monitoring of all pathological conditions. 70%-80% of diagnostic decisions are based on laboratory tests. Correct interpretation of laboratory results allows a doctor to distinguish "healthy" from "diseased".
Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be interpreted in relation to each individual case and family history, clinical findings and the results of other laboratory tests and information. Your personal physician should explain the importance of your test results.
At Diagnostiki Athinon we answer any questions you may have about the test you perform in our laboratory and we contact your doctor to get the best possible medical care.