The measurement of anti-centromeric antibodies is used in the evaluation of patients with clinical signs and symptoms compatible with systemic scleroderma, which may include skin manifestations, Raynaud's phenomenon, and arthralgia.
CREST syndrome is a variant of scleroderma and is characterized by calcification, Raynaud's phenomenon, esophageal dysfunction, scleroderma, and telangiectasia. Anti-centromeric antibodies are present in most patients with CREST syndrome.
Important Note
Laboratory test results are the most important parameter for the diagnosis and monitoring of all pathological conditions. 70%-80% of diagnostic decisions are based on laboratory tests. The correct interpretation of laboratory results allows a doctor to distinguish "healthy" from "diseased".
Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be interpreted in relation to each individual case and family history, clinical findings, and the results of other laboratory tests and information. Your personal physician should explain the importance of your test results.
At Diagnostiki Athinon we answer any questions you may have about the test you perform in our laboratory and we contact your doctor to get the best possible medical care.
