GluRδ2, also known as Glutamate Receptor δ2 or Grid2, is a protein that belongs to the glutamate receptor family. It plays a role in synaptic transmission in the central nervous system, particularly in the cerebellum, where it's involved in the regulation of synaptic plasticity and motor coordination.
Anti-glutamate receptor antibodies are autoantibodies detected in serum and/or cerebrospinal fluid samples of a variety of disorders such as encephalitis, epilepsy, and ataxia. Clinical and experimental studies suggest that these antibodies are not simply epiphenomena and are involved in autoimmune disease pathogenesis.