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Herpes Simplex Virus Type 2 (HSV-2), Molecular Detection

Molecular testing for herpes simplex virus type 2 is used to quickly and accurately diagnose laboratory infections from these viruses.

Herpesviruses (family Herpesviridae) are globally spread, affecting both humans and animals while there are hundreds of different species. Common to all types of herpes viruses is the high level of infection (60-90% of the population are carriers) and their ability to remain latent in the body for long periods.

Herpes Simplex Virus (HSV) is the pathogen that causes bladder rash (herpes simplex and genital herpes), encephalitis, and generalized infant infection (neonatal herpes). Herpes simplex viruses have a double-stranded DNA (dsDNA) genome and have been classified into two different types, the herpes simplex virus type 1 (HSV-1) and the herpes simplex virus type 2 (HSV-2).

Initial herpes simplex virus type 2 infection occurs in the urogenital region (genital type) and can occur regardless of the presence of herpes simplex virus infection 1. The disease occurs with self-inflicted lesions or ulcers that can be accompanied by influenza-like symptoms (fever, swollen lymph nodes). The herpes simplex virus type 2 remains latent in the lumbar ganglia or peripheral tissues, where it can cause episodes of active genital herpes. Neurological complications are much rarer and milder than those of herpes simplex virus type 1. On the other hand, infections of newborn infants (neonatal herpes) in cases of maternal genital herpes have a very high mortality rate. The herpes simplex virus type 2 is usually transmitted by sexual intercourse and therefore, this type of infection is not observed before puberty.



Important Note

Laboratory test results are the most important parameter for the diagnosis and monitoring of all pathological conditions. 70%-80% of diagnostic decisions are based on laboratory tests. The correct interpretation of laboratory results allows a doctor to distinguish "healthy" from "diseased".

Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be interpreted in relation to each individual case and family history, clinical findings, and the results of other laboratory tests and information. Your personal physician should explain the importance of your test results.

At Diagnostiki Athinon we answer any questions you may have about the test you perform in our laboratory and we contact your doctor to get the best possible medical care.

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