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Methadone (MTD), Urine

This test checks the urine for methadone.

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Methadone (dolophine) was first synthesized as a substitute for morphine in Germany during World War II. Methadone is as potent as morphine as an analgesic. Its intended uses in medicine are the management of moderate to severe pain and the detoxification and conservative treatment of opioid addiction. Methadone is excreted in the urine as methadone along with the EDDP and EMDP metabolites. Methadone has a half-life of 15-55 hours and is detected in the urine up to 5-7 days after use. Although methadone is used as a drug for opioid dependence, it does not give a positive reaction to the detection of opioids in the urine.

Physiological actions: Headache, nausea, vomiting, constipation, weight gain, epigastric pain, flushing, sweating, difficulty in urinating, vision problems, swelling, and loss of menstruation.

Psychological actions: Sleepiness, weakness, loss of appetite, dry mouth, mood swings, difficulty in getting or maintaining sleep, and decreased sexual desire or ability.

Toxicity: Depression, seizures, itching, urticaria, rash, dizziness, nausea, sweating, anorexia, vision disorders, bradycardia, palpitations, respiratory depression, lethargy, muscle relaxation, miosis, hypotension, circulatory shock and coma.

Important Note

Laboratory test results are the most important parameter for the diagnosis and monitoring of all pathological conditions. 70%-80% of diagnostic decisions are based on laboratory tests. The correct interpretation of laboratory results allows a doctor to distinguish "healthy" from "diseased".

Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be interpreted in relation to each individual case and family history, clinical findings, and the results of other laboratory tests and information. Your personal physician should explain the importance of your test results.

At Diagnostiki Athinon we answer any questions you may have about the test you perform in our laboratory and we contact your doctor to get the best possible medical care.

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