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Parechoviruses, Molecular Detection

Molecular detection for Parechoviruses is used for laboratory documentation of infections with these viruses.

Parechoviruses, also known as human parechoviruses (HPeVs), are a group of viruses that belong to the Picornaviridae family (RNA viruses). These viruses are primarily known for causing mild to moderate illnesses in humans, particularly in infants and young children. Parechovirus infections are common and typically result in symptoms resembling a cold or mild gastrointestinal illness.

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There are several types of human parechoviruses, with parechovirus type 1 (HPeV-1) and parechovirus type 3 (HPeV-3) being the most commonly identified in human infections.

Parechoviruses are typically transmitted from person to person through direct contact with respiratory secretions (e.g., saliva, mucus) or fecal-oral transmission. They can also be found in the stool of infected individuals.

Infections with parechoviruses can result in a range of symptoms, including fever, runny or stuffy nose, cough, sore throat, diarrhea, and sometimes a rash. In some cases, particularly in infants, parechovirus infections can lead to more serious conditions, such as viral sepsis or central nervous system infections (meningitis or encephalitis). Parechovirus infections are most common in infants and young children, but people of all ages can be infected. While most parechovirus infections are mild and self-limiting, severe cases can occur, especially in infants and individuals with weakened immune systems.

Parechovirus infections can be diagnosed through laboratory testing of samples such as throat swabs, stool samples, or cerebrospinal fluid, depending on the suspected site of infection.

There is no specific antiviral treatment for parechovirus infections. Management typically involves supportive care to relieve symptoms and address any complications, especially in severe cases.

It's important to note that parechovirus infections are typically not as widely recognized as some other viral infections, but they can cause illnesses that may require medical attention, especially in infants and individuals with underlying health conditions.

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