Anti-ovarian antibodies (AOA) are found in 15-50% of patients with early ovarian insufficiency, usually younger than 40 years. Anti-ovarian antibodies react with cells producing steroid hormones such as Leydig cells, in the testes, with the placenta, and often also with the adrenal cortex.
Anti-ovarian antibodies are often found in autoimmune polyendocrine syndrome-1 (APS-1), where adrenal and ovarian insufficiency can coexist. Patients with APS-1 have mutations in the autoimmune regulator gene (AIRE).
A high proportion of women, up to 70%, may develop transient antiviral antibodies during IVF attempts.
Important Note
Laboratory test results are the most important parameter for the diagnosis and monitoring of all pathological conditions. 70%-80% of diagnostic decisions are based on laboratory tests. The correct interpretation of laboratory results allows a doctor to distinguish "healthy" from "diseased".
Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be interpreted in relation to each individual case and family history, clinical findings, and the results of other laboratory tests and information. Your personal physician should explain the importance of your test results.
At Diagnostiki Athinon we answer any questions you may have about the test you perform in our laboratory and we contact your doctor to get the best possible medical care.
