Measurement of the vasoactive intestinal polypeptide is used in the investigation of patients with chronic diarrhea and hypokalaemia and hypochlorhydria.
The vasoactive intestinal polypeptide (VIP) is a gastrointestinal hormone produced by neuroendocrine cells in the small and large intestine, the pancreas, the brain, and the peripheral nervous system. Its actions include stimulation of pancreatic secretion, stimulation of glycogenolysis, inhibition of gastric secretions, stimulation of insulin and glucagon release, induction of peripheral vasodilatation, induction of positive inotropic and chronotropic action on the cardiovascular system, slowdown of gastric motility, stimulation of intestinal chloride secretion and inhibition of intestinal sodium absorption.
Patients with neoplasms secreting vasoactive intestinal polypeptide (VIPomas) have symptoms of diarrhea high in potassium and bicarbonate.
The vasoactive intestinal polypeptide is also abundant in the lungs and is thought to cause bronchodilation.
Important Note
Laboratory test results are the most important parameter for the diagnosis and monitoring of all pathological conditions. 70%-80% of diagnostic decisions are based on laboratory tests. The correct interpretation of laboratory results allows a doctor to distinguish "healthy" from "diseased".
Laboratory test results should not be interpreted from the numerical result of a single analysis. Test results should be interpreted in relation to each individual case and family history, clinical findings, and the results of other laboratory tests and information. Your personal physician should explain the importance of your test results.
At Diagnostiki Athinon we answer any questions you may have about the test you perform in our laboratory and we contact your doctor to get the best possible medical care.
