Heavy metals are found everywhere in the environment and can seriously damage human health. They can damage the central nervous, cardiovascular, gastrointestinal, lungs, kidneys, liver, endocrine glands, and bones. In addition to their direct and toxic effects, certain metals can cause hypersensitivity reactions ("allergy" or delayed type IV hypersensitivity) in sensitive individuals, resulting in responses from the skin, endocrine glands, and immune system.
A metal saliva test can detect which metals from dental fillings or other metal dental implants (e.g., crowns) are released into the saliva.
Heavy Metals in Saliva
Depending on their composition, condition, location, and size, metal dental restoration materials can release varying amounts of metals into saliva and surrounding tissues due to wear and corrosion. In some cases, this can cause local or even generalized inflammation of the gums. Because the metals in saliva end up in the gastrointestinal tract, the gastrointestinal mucosa is exposed and can also be irritated.
However, apart from their local action, the continuous exposure of the intestine to increased concentrations of heavy metals increases the risk of absorption and occurrence of systemic manifestations. Chronic exposure to minerals is a factor in the development of many chronic inflammatory diseases. The association of exposure to heavy metals with conditions such as chronic fatigue syndrome, hypertension, and various neurological disorders is now well established. In addition to the size of the exposure to heavy metals, the patient's sensitivity is also essential for the type and degree of symptoms.
Heavy metals exert their effect on the body in two ways. First, minimal metal concentrations can cause hypersensitivity reactions (type IV immune response). The permanent immune system stimulation from constant exposure to metals can include all aspects of chronic inflammation, such as increased local inflammatory processes, autoimmune reactions, and fatigue. Second, metals such as mercury, cadmium, and palladium have toxic effects even at low doses and inhibit many cellular metabolic processes. Even very low (sub-toxic) concentrations may be of clinical significance, as multiple sources of exposure (from food and water) may enhance the toxicity of the metal. Toxic effects and allergic sensitization to metals occur independently.
To whom Heavy Metals Extended Profile, Saliva is addressed
Studies in experimental animals and epidemiological studies in humans suggest that chronic exposure to heavy metals can cause, among others:
- Attention Deficit Hyperactivity Disorder (ADHD)
- Autistic type disorders
- Depression and mood disorders
- Multiple Sclerosis
- Neurodegenerative diseases (Parkinson's and Alzheimer's diseases)
- Chronic fatigue and feeling of reduced energy
- Infertility
- Cataract
- Hypertension
- Delayed type IV hypersensitivity reactions, such as:
- Psoriasis
- Eczema
- Multiple sclerosis
- Systemic lupus erythematosus
- Sjogren's syndrome
- Thyroiditis
- Gastrointestinal disorders
- Fibromyalgia
- Chronic fatigue syndrome
Checking saliva for metals is a valuable way to assess the body's exposure to various heavy metals due to dental fillings or other dental prostheses in the mouth. The presence of certain metals may justify the presence of local oral reactions (e.g., lichen planus, ulcers, etc.). However, just because a saliva test shows elevated levels of heavy metals does not necessarily mean their levels are high in the rest of the body. For this reason, testing some other biological material for heavy metals (hairs or nails, blood, urine) is also recommended. If these tests are positive, the metals detected in saliva are absorbed into the body.
The primary goal of preventive medicine is to avoid or remove exposure to toxic substances. The saliva test for heavy metals provides immediate proof of exposure due to the wear of dental fillings, and the results can help in the appropriate preventive and therapeutic interventions.
The measurements are performed using the ICP-MS method (Inductively Coupled Plasma Mass Spectrometry), which enables the simultaneous detection of many metals. Its sensitivity and accuracy are significantly better than the conventional atomic absorption method, which can measure metals in concentrations up to 1 in 1015 (1 in 1 quadrillion, ppq)!
